The introduction of polyethylene glycol (PEG) into biomolecule and biosimilar is well known to enhance the stability and pharmacological properties of proteins, peptides, antibody-biosimilar conjugates and small molecule compounds.As a synthetic polymer with high hydrophilicity, PEG is widely used to prolong the circulation time of proteins, increase the aqueous solubility of therapeutic molecules and reduce the immunogenicity of biopharmaceuticals. In many cases, PEG(polyethylene glycol) modification can not only significantly improve the physicochemical properties of the biosimilar, but also alter the pharmacokinetics and pharmacodynamics of the biosimilar. With years of experience in bioconjugation services, Gxene Biotech provides custom PEGylated conjugates and PEGylation services for proteins, peptides, oligonucleotides, and small molecules.
Protein PEGylation Service Procedure:
Service Highlights:
--Rich experience in PEG and protein technology
--Reasonable timeline and cost
--GMP-grade proteins