Protein Modification and Detection Services

As an industry leader in recombinant antibody and protein production, Gxene Biotech offers unrivaled expertise in the research of protein modification and detection. With the combination of an extensive background in biopharmaceutical and proprietary development platforms, we can provide comprehensive protein modification and detection services based on the full understanding of every client’s needs, such as protein purification, GST fusion protein purification, protein sequencing, protein labeling, protein PEGylation and endotoxin testing.
 
Protein Purification Services 
 
Protein purification is vital for the characterization of the function, structure and interactions of the target protein. We can propose a solution to quickly and cost-effectively purify your proteins to your specifications and provides professional scientific support with every step of the way. Our protein purification services include natural and recombinant proteins purification.
 
GST Fusion Protein Purification Services 
 
GST fusion protein has been widely used in recombinant protein expression and production. GST folds rapidly into a stable and highly soluble protein upon translation, so inclusion of the GST tag often promotes greater expression and solubility of recombinant proteins than expression without the tag. GST-tagged fusion proteins also can be purified or detected based on the ability of GST to bind its substrate, glutathione (GSH).
 
Protein Sequencing Services 
 
We have established a comprehensive protein sequencing platform to meet various needs of our clients including N-terminal sequencing and de novo sequencing. Advantages of N-terminal Edman sequencing include high sensitivity, even with picomoles of protein. Proteins can be sequenced in solution, gels or on PVDF blots. If a protein sequence is different from what’s available in the protein sequence databases, de novo sequencing is the only way to get a 100% accurate result.
 
Protein Labeling Services 
 
Gxene Biotech has developed a series of protein labeling techniques and provides personalized solutions designed to supply researchers with the widest choice of labels to meet your research requirements. Such as enzyme conjugation, fluorescent labeling, isotope labeling, PEG labeling, biotinylation, magnetic beads conjugation, quantum dots labeling.
 
Protein PEGylation Services 
 
PEGylation refers to adding polyethylene glycol (PEG) polymer chains onto target molecules to monitor their physiochemical properties. In many cases, protein PEGylation not only significantly improve the physico-chemical properties, but also modify the pharmacokinetics and pharmacodynamics of a drug. KMD Bioscience provides custom PEGylated conjugates and PEGylation services for proteins, peptides, oligonucleotides, and small molecules.
 
Endotoxin Testing Services 
 
We provide endotoxin testing services for clients by the kinetic turbidimetric method. As the concentration of insoluble coagulin increases during the LAL reaction, the turbidity of the reaction mixture increases. We can also provide a gel-clot method for the detection of endotoxin levels in samples. Our experienced specialists can help improve the compliance and efficiency of your endotoxin testing program and help you to achieve control, consistency and precision.
As an industry leader in recombinant antibody and protein production, Gxene Biotech offers unrivaled expertise in the research of protein modification and detection. With the combination of an extensive background in biopharmaceutical and proprietary development platforms, we can provide comprehensive protein modification and detection services based on the full understanding of every client’s needs, such as protein purification, GST fusion protein purification, protein sequencing, protein labeling, protein PEGylation and endotoxin testing.
 
Protein Purification Services 
 
Protein purification is vital for the characterization of the function, structure and interactions of the target protein. We can propose a solution to quickly and cost-effectively purify your proteins to your specifications and provides professional scientific support with every step of the way. Our protein purification services include natural and recombinant proteins purification.
 
GST Fusion Protein Purification Services 
 
GST fusion protein has been widely used in recombinant protein expression and production. GST folds rapidly into a stable and highly soluble protein upon translation, so inclusion of the GST tag often promotes greater expression and solubility of recombinant proteins than expression without the tag. GST-tagged fusion proteins also can be purified or detected based on the ability of GST to bind its substrate, glutathione (GSH).
 
Protein Sequencing Services 
 
We have established a comprehensive protein sequencing platform to meet various needs of our clients including N-terminal sequencing and de novo sequencing. Advantages of N-terminal Edman sequencing include high sensitivity, even with picomoles of protein. Proteins can be sequenced in solution, gels or on PVDF blots. If a protein sequence is different from what’s available in the protein sequence databases, de novo sequencing is the only way to get a 100% accurate result.
 
Protein Labeling Services 
 
Gxene Biotech has developed a series of protein labeling techniques and provides personalized solutions designed to supply researchers with the widest choice of labels to meet your research requirements. Such as enzyme conjugation, fluorescent labeling, isotope labeling, PEG labeling, biotinylation, magnetic beads conjugation, quantum dots labeling.
 
Protein PEGylation Services 
 
PEGylation refers to adding polyethylene glycol (PEG) polymer chains onto target molecules to monitor their physiochemical properties. In many cases, protein PEGylation not only significantly improve the physico-chemical properties, but also modify the pharmacokinetics and pharmacodynamics of a drug. KMD Bioscience provides custom PEGylated conjugates and PEGylation services for proteins, peptides, oligonucleotides, and small molecules.
 
Endotoxin Testing Services 
 
We provide endotoxin testing services for clients by the kinetic turbidimetric method. As the concentration of insoluble coagulin increases during the LAL reaction, the turbidity of the reaction mixture increases. We can also provide a gel-clot method for the detection of endotoxin levels in samples. Our experienced specialists can help improve the compliance and efficiency of your endotoxin testing program and help you to achieve control, consistency and precision.