Cynomolgus DC SIGN重组蛋白是一种重要的病原体识别受体,在未成熟树突状细胞(DC)上表达,对于启动初级免疫反应至关重要。DC-SIGN(Cluster of Differentiation 209,CD209)通过介导溶酶体室内病原体的内吞作用和随后的降解,在病原体识别中发挥关键作用。此外,DC-SIGN在细胞粘附和病原体识别中扮演着重要角色,能够识别包括HIV-1、结核分枝杆菌、埃博拉病毒等多种病原体,显示了其在免疫学研究中的广泛应用价值。
种属:Cynomolgus;
Uniprot ID:A0A2K5WSP4;
纯度:≥95%;
表达系统:293F;
表达区间:62-406 aa
(XP_015296329.1);
蛋白标签:C-His tag;
分子量:44-54 kDa;
内毒素:<0.1EU/ug |
Alternate Names:CD209 antigendendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbingnon-integrin; CD209 molecule; CD209; CDSIGNHIV gpl20-binding protein; CLEC4L; CLEC4LC-type lectin domain family 4 member L; DCSIGN; DC-SIGN; DC-SIGN1; DC-SIGN1C-type lectin domain family 4, member L; DC-SIGNMGC129965; Dendritic cell-specific ICAM-3-grabbing non-integrin 1