研究方向

Pentraxin 3/TSG-14 蛋白是 pentraxin 蛋白家族的成员，由该基因编码。其表达是由炎症细胞因子响应炎症刺激而诱导的，特别是在各种间充质和上皮细胞类型中，包括内皮细胞和单核吞噬细胞。这种蛋白质在促进纤维细胞分化中发挥着至关重要的作用，并积极参与调节炎症和补体激活。此外，它还有助于血管生成和组织重塑。值得注意的是，Pentraxin 3/TSG-14 可作为多种炎症状况的生物标志物，反映了其潜在的临床意义。该基因表现出偏向表达，在骨髓 (RPKM 32.2)、阑尾 (RPKM 24.8) 和其他六个组织中表达水平升高，突出了其在多个器官的各种生理环境中的特定参与。

• 纯度：
  >95% (SDS-PAGE)
• 基因名：
  PTX3
• Uniprot No.：
  P26022
• 别名：
  AI607804; Pentaxin 3; Pentaxin-related protein PTX3; Pentraxin 3 long; Pentraxin-related gene; Pentraxin-related gene rapidly induced by IL-1 beta; Pentraxin-related protein PTX3; PTX3; PTX3_HUMAN; TNF alpha-induced protein 5; TNFAIP5; TSG-14; TSG14; Tumor necrosis factor alpha-induced protein 5; Tumor necrosis factor-inducible gene 14 protein; Tumor necrosis factor-inducible protein TSG-14
• 种属：
  Homo sapiens (Human)
• 蛋白长度：
  Full Length of Mature Protein
• 表达区域：
  18-381
• 氨基酸序列
  ENS DDYDLMYVNL DNEIDNGLHP TEDPTPCACG QEHSEWDKLF IMLENSQMRE RMLLQATDDV LRGELQRLRE ELGRLAESLA RPCAPGAPAE ARLTSALDEL LQATRDAGRR LARMEGAEAQ RPEEAGRALA AVLEELRQTR ADLHAVQGWA ARSWLPAGCE TAILFPMRSK KIFGSVHPVR PMRLESFSAC IWVKATDVLN KTILFSYGTK RNPYEIQLYL SYQSIVFVVG GEENKLVAEA MVSLGRWTHL CGTWNSEEGL TSLWVNGELA ATTVEMATGH IVPEGGILQI GQEKNGCCVG GGFDETLAFS GRLTGFNIWD SVLSNEEIRE TGGAESCHIR GNIVGWGVTE IQPHGGAQYV S
• 蛋白标签：
  Tag type will be determined during the manufacturing process.
  

  The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
• 产品提供形式：
  Lyophilized powder
  Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
• 复溶：
  We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
• 储存条件：
  Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• 保质期：
  The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
  Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.